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Pressure Regulator Selection Guides

Choosing the Correct Regulator Based on Flow, Pressure, and Application Needs

Semiconductor gas delivery systems require regulators that can deliver stable outlet pressure, ultra-clean wetted surfaces, and high reliability across a wide range of gas types — from inert bulk gases to toxic corrosive process gases.

VPC regulators are built with 316L VAR / VIM stainless steel, Hastelloy options for corrosives, and Class-100 cleanroom assembly, giving them compatibility with applications from Bulk Gas → Facility → VMB/VMP → Hook-Up → Tool-Level Control.

This Selection Guide explains each regulator series in simple, application-driven language, making it easy for buyers and decision makers to choose the correct model.

1. Bulk Gas / Cylinder Regulators (High Pressure to Low Pressure)

VPC1000 Series — High Pressure, General-Purpose Precision

Best for: Gas cylinders (O₂, H₂, N₂, CO₂, Ar), high inlet pressures up to 4,000 psig, labs, industrial, and high-pressure semiconductor applications.

Why Choose VPC1000

  • Handles high inlet pressures safely
  • Compatible with both corrosive and inert gases
  • Clean internal surface (Ra 10–15 μin)
  • Cv = 0.06–0.2 for precise cylinder pressure control

Typical Use

  • Gas cylinder at source
  • Transition from cylinder to facility sub-main piping
VPC1000 Series Regulator

VPC2000 Series — High Purity, High Flow Facility Regulator

Best for: Facility main and sub-main piping for inert and corrosive gases, high purity bulk gas distribution.

Why Choose VPC2000

  • Electropolished internal passages for high purity
  • Autogenous welds with no virtual leak cavities
  • Cv up to 1.0 for robust facility-level flow
  • Handles toxic, inert, or corrosive gases reliably

Typical Use

  • Facility distribution lines (main and sub-main)
  • Bulk N₂, CDA, and process gas distribution
VPC2000 Series Regulator

VPC2500 Series — Higher Flow Version of VPC2000

Best for: Same applications as VPC2000 but requiring even larger flow, especially facility-level main gas supply to VMB/VMP.

Why Choose VPC2500

  • Cv up to 1.8
  • Same electropolished, welded high-purity design as VPC2000

Typical Use

  • High-demand sub-main lines
  • High-volume inert gas supply
VPC2500 Series Regulator

VPC3000 Series — Ultra High Flow Facility Regulator

Best for: Very large flow (Cv = 5 / 10 / 15 / 20) for bulk supply of N₂, CDA, and inert gases in cleanroom facility distribution.

Why Choose VPC3000

  • The highest-flow regulator in the facility series
  • Designed specifically for main-line pressure reduction

Typical Use

  • Main trunk lines and gas yards
  • N₂ blanketing and high-volume purging
VPC3000 Series Regulator

VPC7500 Series — Two-Stage Regulator (Most Stable Delivery)

Best for: Applications needing extremely stable outlet pressure with large inlet pressure drops (e.g., full → empty cylinders), HP and UHP specialty gas cylinders.

Why Choose VPC7500

  • Extremely low supply pressure effect
  • Best stability (0.06 psig / 100 psig inlet change)
  • Ideal for toxic gases (PH₃, AsH₃, B₂H₆, SiH₄ mixtures)

Typical Use

  • Silane / PH₃ / AsH₃ cylinders
  • High-end specialty gases used in semiconductor processes
VPC7500 Series Regulator

2. Point-of-Use / Hook-Up Regulators (Precise, Local Pressure Control)

VPC4000 Series — High-Performance Point-of-Use Regulator

Best for: Hook-up lines, process equipment inlet, and sensitive process tools needing stable pressure.

Why Choose VPC4000

  • Cv = 1.0
  • Designed specifically for modern semiconductor tools
  • Ultra-clean internal passages (Ra = 10 μin)
  • Handles corrosive, toxic, and specialty gases

Typical Use

  • AMAT / TEL / Lam tools inlet
  • UHP process tool pressure regulation
VPC4000 Series Regulator

VPC5000 Series — Ultra Clean, High Integrity Regulator

Best for: UHP gas cabinets, extremely sensitive processes requiring zero contamination, ultra clean and leak-tight specialty gas control.

Why Choose VPC5000

  • Metal-to-metal diaphragm seal
  • Minimizes particle generation
  • Best choice for corrosive specialty gases

Typical Use

  • Gas cabinet outlet
  • High purity process gas lines
  • Replacement for Veriflo and Tescom regulators
VPC5000 Series Regulator

3. Micro / Compact Regulators (Surface Mount & Miniature Tools)

VPC Micro Series — Compact, High Purity Regulator

Best for: Small footprint tools, hook-up and equipment modules, low internal volume and fast response systems.

Why Choose VPC Micro Series

  • Cv = 0.06, flow up to 100 slpm
  • Very low internal volume for fast response
  • Matches Veriflo Quantum dimensions for easy retrofit

Typical Use

  • Compact tools and hook-up modules
  • Equipment where space and internal volume are limited
VPC Micro Series Regulator

VPC Micro SM — Surface Mount Micro Regulator

Best for: Surface-mount (SMS) modular manifold panels and high-density gas delivery modules.

Why Choose VPC Micro SM

  • Meets SEMI modular interface standards
  • Smallest wetted volume among micro regulators
  • Easy retrofit on modular gas box platforms

Typical Use

  • Surface-mount manifold panels
  • High-density gas boxes and compact modules
VPC Micro SM Surface Mount Regulator

Quick Decision Guide

  • If you are reducing pressure directly from high-pressure cylinders → VPC1000.
  • If you need a high-purity, high-flow regulator for facility distribution → VPC2000.
  • If your facility requires more flow than VPC2000 can provide → VPC2500.
  • If you need ultra-high-flow regulation for main facility distribution → VPC3000.
  • If you require high-performance pressure control at the tool inlet → VPC4000.
  • If you need UHP point-of-use or gas-cabinet outlet regulation → VPC4000 or VPC5000 depending on purity requirements.
  • If your inlet pressure fluctuates heavily → choose a two-stage regulator such as VPC7500.
  • If you need compact size, high purity, and fast response → VPC Micro.
  • If you need a surface-mount solution for SMS manifolds or compact modular gas panels → VPC Micro SM.
Flow Capacity (Cv) Regulator Series Application Use / Line Inlet / Outlet Pressure Range Connector Size
0.15–0.2 VPC1000 Bulk Gas system with non-toxic gas Gas cylinder, sub pipe 4000 PSIG / 30, 100, 300, 500 PSIG ¼” to ½”
0.85 VPC2000 Main & sub pipe 500 PSIG / 30, 150 PSIG ½” to ¾”
1.8 VPC2500 Main & sub pipe 500 PSIG / 30, 150 PSIG ½” to 25A
5.0–8.0 VPC3000 Main pipe 300 PSIG / 50, 250 PSIG 1” to 25A
0.06–1.55 VPC4000 Specialty gas system Hook-up, point of use 250 PSIG / Vacuum to 30, 100 PSIG ½” to ½”
0.06 VPC5000 Gas cabinets 4000 PSIG / 20, 100, 300, 500 PSIG ½” to ½”
0.06 VPC Micro Hook-up / equipment 250 PSIG / Vacuum to 30, 100 PSIG ¼”


  • Gas Cylinder (High Pressure Input) → Choose VPC1000 (single stage) → VPC2000 (standard high purity) → VPC2500 (higher flow) → VPC3000 (very large flow) → VPC7500 (two-stage, highest stability).
  • Point-of-Use (Tool Hook-Up) → Choose VPC4000 for modern semiconductor tools, or VPC5000 for UHP gas cabinets and corrosive gases.
  • Compact Equipment / Surface Mount → Choose VPC Micro for compact tools, or VPC Micro SM for surface-mount SMS manifolds.